abstract：BACKGROUND AND AIM:Baclofen, a γ-aminobutyric acid receptor agonist, has been shown to reduce the episodes of gastroesophageal reflux (GER) by reducing the incidence of transient lower esophageal sphincter relaxations. Although baclofen has been shown to reduce reflux symptoms in adults, data in pediatric patients are ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Vadlamudi NB,Hitch MC,Dimmitt RA,Thame KA

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to study the effect of continued Lactobacillus rhamnosus GG strain (LGG) feeding on rotavirus gastroenteritis in the gnotobiotic (Gn) pig model of virulent human rotavirus (HRV) infection. METHODS:Gn pigs were assigned to treatment groups: mock control, LGG only, HRV only, or LGG pl...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Liu F,Li G,Wen K,Wu S,Zhang Y,Bui T,Yang X,Kocher J,Sun J,Jortner B,Yuan L

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the accuracy of reduced-dose ¹³C-urea breath test (¹³C-UBT) and early sampling of exhaled breath for the detection of Helicobacter pylori infection in children and adolescents. METHODS:Patients up to 20 years old that underwent upper gastrointestinal endoscopy with gastr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Pacheco SL,Ogata SK,Machado RS,Patrício FR,Pardo ML,Kawakami E

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Endoscopic retrograde cholangiopancreatography (ERCP) is increasingly being used in the evaluation and management of biliary and pancreatic disorders in children. The aim of this study was to review the pediatric ERCP experience of a large academic referral center affiliated with a tertiary care children's h...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Enestvedt BK,Tofani C,Lee DY,Abraham M,Shah P,Chandrasekhara V,Ginsberg GG,Long W,Ahmad N,Jaffe DL,Mamula P,Kochman ML

更新日期：2013-11-01 00:00:00

abstract：:Portal vein thrombosis (PVT) is a common cause of portal hypertension in children. Predisposing conditions for PVT are obscure in more than half of the cases. Variceal bleeding and splenomegaly are the most frequent initial manifestations. Radiologic imaging studies are the mainstay for diagnosis. Treatment includes p...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Giouleme O,Theocharidou E

更新日期：2013-10-01 00:00:00

abstract：AIM:Anti-neutrophil cytoplasmic antibodies (ANCAs) detected by indirect immunofluorescence have been found in patients with inflammatory bowel disease (IBD). Nevertheless, specific antibodies against proteinase-3 (PR3) are rare in this context. METHODS:Sera from 30 consecutive pediatric patients with IBD were evaluate...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Van Biervliet S,Bonroy C,Vande Velde S,De Bruyne R,Van Winckel M,Peeters H,Delanghe J,Stove V,De Vos M

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:The present guidelines of the American Academy of Pediatrics recommend that osmolarity not exceed 450 mOsm/kg (or approximately an osmolarity of 400 mOsm/L) for breast milk or infant formulae, to minimize the risk factors for necrotizing enterocolitis. A commercial protein supplement has been developed to me...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kreissl A,Zwiauer V,Repa A,Binder C,Haninger N,Jilma B,Berger A,Haiden N

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:The present understanding of inflammatory bowel disease pathogenesis mainly relies on studies of adult patients. Therefore, we studied the balance between T-effector and regulatory cells in pediatric inflammatory bowel disease. METHODS:Quantitative polymerase chain reaction and immunohistochemistry served to...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hölttä V,Klemetti P,Salo HM,Koivusalo A,Pakarinen M,Westerholm-Ormio M,Kolho KL,Vaarala O

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVES:The aims of the study were to perform a retrospective observational review of the present management and outcome of cholestatic pruritus in children with Alagille syndrome (AGS) at King's College Hospital and to use results to inform appropriate guidelines. METHODS:A retrospective review of 62 patients diag...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kronsten V,Fitzpatrick E,Baker A

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVES:It is presently recommended that oral feeding be started in premature infants as soon as possible, often at an age at which nasal continuous positive airway pressure (nCPAP) is still required for ventilatory support. Our previous data showed that application of nCPAP up to 10 cmH2O in full-term lambs had no ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Djeddi D,Cantin D,Samson N,Tian H,Praud JP

更新日期：2013-08-01 00:00:00

abstract：:This clinical report aims to review key self-management and adherence issues in pediatric inflammatory bowel disease (IBD) and to provide recommendations for health care providers regarding evidence-based assessment and treatment approaches to promote optimal self-management. Self-management difficulties in the form o...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hommel KA,Greenley RN,Maddux MH,Gray WN,Mackner LM

更新日期：2013-08-01 00:00:00

abstract：:Constipation is a common problem in children worldwide. It can also be a chronic problem persisting for many months to years. Successful treatment of constipation requires long-term use of laxatives. Commonly used laxatives in children include milk of magnesia, lactulose, mineral oil, and polyethylene glycol. Compared...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Alper A,Pashankar DS

更新日期：2013-08-01 00:00:00

abstract：:Growth charts are essential for evaluating children's health including their nutrition; however, the evaluation of child growth trajectories and consequently the decision to intervene are highly dependent on the growth charts used. The aim of this discussion paper of the European Society for Paediatric Gastroenterolog...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Turck D,Michaelsen KF,Shamir R,Braegger C,Campoy C,Colomb V,Decsi T,Domellöf M,Fewtrell M,Kolacek S,Mihatsch W,Moreno LA,van Goudoever J

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Many mathematical equations based on height have been developed to estimate the esophageal length (EL) in children. The aim of this study was to confirm whether the preexisting and most frequently used equation by Strobel et al is accurate in calculating the EL in our pediatric population. Our...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Moreau B,Kambites S,Lévesque D

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVES:A sharp increase in paediatric (younger than 16 years) inflammatory bowel disease (IBD) incidence was observed in northern Stockholm County, Sweden, in 1990-2001. The increasing incidence was primarily explained by a rising incidence of Crohn disease (CD). Here, we present an update on the trends in incidenc...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Malmborg P,Grahnquist L,Lindholm J,Montgomery S,Hildebrand H

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In the last 10 years, there have been an increasing number of case reports concerning gastrointestinal injury related to magnet ingestions; however, the magnitude of the problem remains to be clearly defined. The aim of the study was to examine the epidemiology of magnet ingestion-related emerg...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Abbas MI,Oliva-Hemker M,Choi J,Lustik M,Gilger MA,Noel RA,Schwarz K,Nylund CM

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:Oxidative stress has been implicated in the development of nonalcoholic fatty liver disease (NAFLD) and progression to the more severe form, nonalcoholic steatohepatitis (NASH), in children. We aimed to study the clinical correlation between bilirubin, a potent endogenous antioxidant with cytoprotective prop...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Puri K,Nobili V,Melville K,Corte CD,Sartorelli MR,Lopez R,Feldstein AE,Alkhouri N

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:LIPA gene mutations result in deficiency of lysosomal acid lipase and present phenotypically as Wolman disease or cholesteryl ester storage disease (CESD) depending on the level of deficiency. Patients with CESD may often be misdiagnosed because symptoms may be nonspecific. Symptoms may present in infancy if ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Zhang B,Porto AF

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:Congenital portosystemic shunts (CPSSs) are rare but increasingly recognized as a cause of important multisystem morbidity. We present new cases and a systematic literature review and propose an algorithm for the identification and care of affected patients. METHODS:We reviewed the charts of consecutive pat...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sokollik C,Bandsma RH,Gana JC,van den Heuvel M,Ling SC

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:Intestinal failure (IF) is a common consequence of neonatal small bowel pathology. In our experience, bowel dilatation is often responsible for the IF state in patients who fail to adapt despite adequate residual bowel length. The aim of the present study was to investigate the role of surgery to reduce bowe...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Almond SL,Haveliwala Z,Khalil B,Morabito A

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Despite studies indicating that vitamin D intake among Swedish children does not meet the recommendation, little is known of their vitamin D status. The aim of the present study was to examine vitamin D status in preschool-age children in relation to vitamin D intake, season, body mass index, a...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Öhlund I,Silfverdal SA,Hernell O,Lind T

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVES:Aim of the study was to evaluate the response to hepatitis A and B vaccination in pediatric patients with inflammatory bowel disease (IBD). METHODS:A total of 47 patients with IBD (25 ulcerative colitis, 14 Crohn's disease, and 8 indeterminate colitis) ages 3 to 17 years were compared with 50 healthy age- a...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Urganci N,Kalyoncu D

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVES:International trends in incidence and outcomes of biliary atresia (BA) are controversial and a wide range of estimates have been reported worldwide. We reviewed the population-based literature to assess international variation of BA incidence and outcomes, and to assess the evidence for seasonal variation in...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Jimenez-Rivera C,Jolin-Dahel KS,Fortinsky KJ,Gozdyra P,Benchimol EI

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND AIM:Pediatric gastroenterology is the only pediatric subspecialty with nutrition as part of its official curriculum and objective; however, pediatric gastroenterology fellows believe that their baseline knowledge in nutrition is suboptimal. The purpose of the present study was to assess the perceived eff...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Lin HC,Kahana D,Vos MB,Black D,Port Z,Shulman R,Scheimann A,Mascarenhas MR

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to describe the relation between sensory issues and medical complexity in a series of patients presenting to an outpatient multidisciplinary feeding team for evaluation, by a standardized measure of sensory-processing abilities. METHODS:A retrospective chart review of all of the pat...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Davis AM,Bruce AS,Khasawneh R,Schulz T,Fox C,Dunn W

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:Little is known about the effect of diet on the oral microbiota of infants, although diet is known to affect the gut microbiota. The aims of the present study were to compare the oral microbiota in breast-fed and formula-fed infants, and investigate growth inhibition of streptococci by infant-isolated lactob...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Holgerson PL,Vestman NR,Claesson R,Ohman C,Domellöf M,Tanner AC,Hernell O,Johansson I

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:Discordance exists between outcomes of endoscopy, multichannel intraluminal impedance monitoring (pH-MII), MII baselines, and gastroesophageal reflux symptoms. The aim of the present study was to determine the association between endoscopy, pH-MII and MII baselines, in children with gastroesophageal reflux s...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： van der Pol RJ,Loots CM,Peeters L,Vandenplas Y,Hauser B,Devreker T,Omari TI,Benninga MA,van Wijk MP

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the tolerability, safety, and efficacy of polyethylene glycol (PEG) 3350 without electrolytes as a 1-day bowel preparation for colonoscopy in children. METHODS:A prospective study of 45 children undergoing colonoscopy prescribed PEG 3350 without electrolytes mixed with a ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Walia R,Steffen R,Feinberg L,Worley S,Mahajan L

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:Patients with inflammatory bowel disease (IBD) are at risk for vitamin and mineral deficiencies because of long-term inflammation in the gut mucosa and decreased oral intake. The aim of the study is to investigate the prevalence of vitamin and zinc deficiencies in patients with newly diagnosed IBD compared w...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Alkhouri RH,Hashmi H,Baker RD,Gelfond D,Baker SS

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIM:Distinguishing biliary atresia (BA) from other causes of neonatal cholestasis (NC) is challenging. Continuous BreathID C-methacetin breath test (MBT) is a novel method that determines liver function. Methacetin is metabolized uniquely by the liver and CO2 is measured passively, through a nasal cannul...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Shteyer E,Lalazar G,Hemed N,Pappo O,Granot E,Yerushalmi B,Gross E

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to evaluate diagnostic performance and actual costs in clinical practice of immumoglobulin (Ig)G/IgA deamidated gliadin peptide antibodies (DGP) as a complement to IgA antibodies against tissue transglutaminase (tTG) for the diagnosis of pediatric celiac disease (CD). METHOD...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Olen O,Gudjónsdóttir AH,Browaldh L,Hessami M,Elvin K,Liedberg AS,Neovius M,Grahnquist L

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:For the pediatric population, upper reference limits (URLs) for aminotransferase levels have not been established. The prevalence of high aminotransferase levels provides important information regarding the burden of liver disease in the current childhood obesity endemic. METHODS:We set the URL of alanine a...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Park SH,Park HY,Kang JW,Park J,Shin KJ

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:In the present study, we evaluated the effect of transforming growth factor-beta 2 (TGF-β2)-enriched diet on enterocyte turnover and correlated it with TGF-β2 receptor expression along the villus-crypt axis in a rat model of short bowel syndrome (SBS). METHODS:CaCo-2 cells were incubated with increasing con...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sukhotnik I,Lulu SB,Pollak Y,Bejar J,Coran AG,Mogilner JG

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:Wireless capsule endoscopy (WCE) is an increasingly used procedure for visualization of the small intestine. One challenge in pediatric WCE is the placement of the capsule in a population unable to swallow it for a variety of reasons. Here we present a novel use of the real-time (RT) viewer in the endoscopic...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bass LM,Misiewicz L

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:Polyethylene glycol (PEG) is a frequently used laxative agent. It is unknown, however, whether PEG affects the absorptive capacity of the intestine. Reduced lipid (dietary fat and cholesterol) absorption induced by long-term PEG treatment could negatively affect growth in children. We tested whether PEG acce...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： van der Wulp MY,Cuperus FJ,Stellaard F,van Dijk TH,Dekker J,Rings EH,Groen AK,Verkade HJ

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:Because of a variable clinical picture, most children with celiac disease remain unrecognized without active serologic screening. Because, however, many patients are asymptomatic, the justification for screening remains unclear. We assessed health and well-being and the effect of a 1-year gluten-free diet in...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kinos S,Kurppa K,Ukkola A,Collin P,Lähdeaho ML,Huhtala H,Kekkonen L,Mäki M,Kaukinen K

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to describe the prevalence of childhood constipation, stool characteristics, and their relationship with toilet training and age of introduction of cow's milk. METHODS:A total of 4231 children born in 2004, from a birth cohort study, were assessed at 12, 24, and 48 months of...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Mota DM,Barros AJ,Santos I,Matijasevich A

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Pediatric ulcerative colitis (UC) shares many features with adult-onset disease but there are some unique considerations; therefore, therapeutic approaches have to be adapted to these particular needs. We aimed to formulate guidelines for managing UC in children based on a systematic review (SR) of ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Turner D,Levine A,Escher JC,Griffiths AM,Russell RK,Dignass A,Dias JA,Bronsky J,Braegger CP,Cucchiara S,de Ridder L,Fagerberg UL,Hussey S,Hugot JP,Kolacek S,Kolho KL,Lionetti P,Paerregaard A,Potapov A,Rintala R,Se

更新日期：2012-09-01 00:00:00

abstract：:Severity scores are used to predict the outcome of acute pancreatitis (AP). Several scores are used in adult patients, but none has been thoroughly validated for specific use in paediatric patients. We retrospectively collected data from 48 children with AP (13 severe and 35 mild). The main causes were trauma (23%), i...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fabre A,Petit P,Gaudart J,Mas E,Vial J,Olives JP,Sarles J

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to evaluate whether polymorphisms of the mannose-binding lectin (MBL-2) gene and MBL serum levels on admission to neonatal intensive care unit are associated with necrotizing enterocolitis (NEC) in preterm infants and to verify MBL expression in NEC bowels. METHODS:In this r...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Prencipe G,Azzari C,Moriondo M,Devito R,Inglese R,Pezzullo M,Piersigilli F,Trucchi A,De Benedetti F,Auriti C

更新日期：2012-08-01 00:00:00